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Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline

原文:2020年 发布于 American Society of Clinical Oncology 浏览量:259 原文链接

作者: American Society of Clinical Oncology

归属分类: 所属人体系统: 消化 | 分类: 食管肿瘤

关键词: Esophageal Carcinoma Advanced Locally Treatment

指南简介

Purpose

To develop an evidence-based clinical practice guideline to assist in clinical decision making for patients with locally advanced esophageal cancer.

Methods

ASCO convened an Expert Panel to conduct a systematic review of the more recently published literature (1999-2019) on therapy options for patients with locally advanced esophageal cancer and provide recommended care options for this patient population.

Results

Seventeen randomized controlled trials met the inclusion criteria. Where possible, data were extracted separately for squamous cell carcinoma and adenocarcinoma.

Recommendations

Multimodality therapy for patients with locally advanced esophageal carcinoma is recommended. For the subgroup of patients with adenocarcinoma, preoperative chemoradiotherapy or perioperative chemotherapy should be offered. For the subgroup of patients with squamous cell carcinoma, preoperative chemoradiotherapy or chemoradiotherapy without surgery should be offered. Additional subgroup considerations are provided to assist with implementation of these recommendations.